NFL Quarterback Club 2001 for the Nintendo 64 is a sports genre video game that simulates American football. Developed by Iguana Entertainment and published by Acclaim Sports, it features updated rosters from the 2000 NFL season. Players can step into the shoes of their favorite NFL quarterbacks, utilizing a range of plays and strategies to outmaneuver the opposition on the gridiron. With a mix of arcade and realistic football gameplay, modes include Season, Exhibition, and the signature Quarterback Challenge, testing skills in precision passing and timed drills.