Despicable Me: The Game for Nintendo Wii is an action-adventure platformer inspired by the animated film Despicable Me. Players take on the role of the film's protagonist, Gru, as they plan and execute heists to prove they are the greatest supervillain in the world. The game features a mix of puzzles, combat, and gadget-based gameplay, allowing players to use an array of whimsical weapons and tools. With the minions at their disposal, players navigate through various levels to accomplish missions and defeat rival villains.